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Ansamitocin P-3' showed potential antineoplastic and antimitotic activity
18 nM and 8 nM
Formula: C7H3Br3O3
Quintana M
an aryloxyisobutyric acid derivate with antihyperlipidemic activity
Sildenafil Catalog No.:M10317-10 Ansamitocin P-3' showed potential antineoplasticSildenafil is a selective inhibitor of PDE5 (type 5 cGMP phosphodiesterase) which catalyzes the hydrolysis of 3',5' cyclic guanosine monophosphate (cGMP). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro , synapto and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. Sildenafil has also been shown to prevent indomethacin induced small intestinal ulceration formation through an NO cGMP dependent